The no-reflow phenomenon in coronary arteries

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The no reflow phenomenon in the coronary arteries.

In the last twenty years, the treatment of coronary heart disease with cardiac catheterization has greatly advanced. This therapeutic approach has had unexpected side effects, however, for which solutions must be found, particularly in the are of interventional cardiology. The “noreflow” phenomenon, a side effect, is an uncommon and critical occurrence and, if not reversed, causes a high rate o...

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No-reflow phenomenon.

To the Editor: In reviewing no-reflow, Rezkalla and Kloner1 indicted injuryinduced microvascular changes, but did not mention spasm of resistance vessels, which might be the basic mechanism of no-reflow. I proposed in 1971 that no-reflow (“stasis”) is due to ischemic injury-induced spasm, and the evidence seemed convincing.2 Short coronary occlusions reversed no-reflow, and this was interpreted...

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'No-reflow' phenomenon.

A 57-year-old man presented with new anginal symptoms nine years after three-vessel coronary artery bypass grafting. Cardiac catherization revealed severely and diffusely diseased saphenous vein graft to the obtuse marginal coronary artery. Percutaneous coronary intervention was complicated by the ‘no-reflow’ phenomenon. The patient suffered a periprocedural myocardial infarction (peak troponin...

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No-reflow phenomenon.

Because total coronary artery occlusion was found in the early hours of transmural myocardial infarction, most of our research interest and treatment strategies focus on epicardial coronary arteries.1 Little attention, however, is paid to the coronary microvasculature. When a coronary artery is occluded, detrimental changes occur in the cardiac capillaries and arterioles. After relief of the oc...

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Predicting the no-reflow phenomenon following successful percutaneous coronary intervention.

In the setting of acute myocardial infarction, early and adequate reopening of an infarct-related artery is not necessarily followed by a complete restoration of myocardial perfusion. This condition is usually defined as 'no-reflow'. The pathophysiology of no-reflow is multifactorial since extravascular compression, microvascular vasoconstriction, embolization during percutaneous coronary inter...

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ژورنال

عنوان ژورنال: Journal of Thrombosis and Haemostasis

سال: 2004

ISSN: 1538-7933,1538-7836

DOI: 10.1111/j.1538-7836.2004.00898.x